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Unlike most diet pills on the market, this new pill called fexaramine does not dissolve into the blood like appetite suppressants or caffeine-based diet drugs, but remains in the intestines, causing fewer side effects. It sends out the same signals that byy happen when you eat a lot of food, so the body starts clearing out space to store it. But there are no calories and no change in appetite," xiet Ronald Evansdirector of the Salk Institute's Gene Expression Laboratory in the US.
Evans' laboratory has spent nearly two decades studying the farensoid X receptor FXRa protein that plays a role in how the body releases bile acids from the liver, digests food and stores fats and sugars. The human body turns on FXR at the beginning of a meal to prepare for an influx of food. Evans and his colleagues developed the fexaramine compound by departing from the drug scaffold that most pharmaceutical companies typically pursue when targeting FXR.
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